Author(s) Details:
Avraham Mayevsky
The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 5290092, Israel.
Michael Tolmasov
The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 5290092, Israel.
Mira Mandelbaum
The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 5290092, Israel.
This section is a part of the chapter: Real Time Assessment of Patients’ Body Oxygen Balance and Tissue Metabolic Score (TMS)
The formation of ATP depends on the sufficiency of the substrate (i.e. glucose) and oxygen supply to the tissue by the blood flow and hemoglobin oxygenation in the microcirculation (Fig. 4) as well as on the integrity of mitochondrial activity (Mayevsky et al., 2018). Without a sufficient supply of ATP, cells cannot function properly and can ultimately die. Since most of the energy consumed by tissues is dependent upon the availability of oxygen, under normal mitochondrial function, there is a high coupling between oxygen supply and energy production. When mitochondrial activity is damaged, due to various reasons, this coupling is disrupted.
How to Cite
Mayevsky, A., Tolmasov, M., & Mandelbaum, M. (2025). Real Time Assessment of Patients’ Body Oxygen Balance and Tissue Metabolic Score (TMS). Medical Science: Trends and Innovations Vol. 4, 101–142. https://doi.org/10.9734/bpi/msti/v4/4146